Melissa Moss, PhD
Core Investigator, Cellular and Molecular Biomarker Core
Professor and Chair, Department of Chemical Engineering
Professor, Department of Biomedical Engineering
University of South Carolina
Biography
Professor Moss received her doctorate in Chemical Engineering from the University of Kentucky and completed postdoctoral training in Biochemistry and Neuroscience at the Mayo Clinic. She joined the Chemical Engineering faculty at South Carolina in 2004, where she now serves as Chair. In addition, she is a faculty member and previous Director of the Biomedical Engineering Program. She has published more than 45 peer-reviewed manuscripts. Research within Professor Moss’ laboratory focuses on the identification of early Alzheimer’s disease (AD) biomarkers and the development of novel AD therapeutics. In the area of early biomarker detection, her laboratory is developing novel biosensing approaches that leverage the sensitivity of endothelial cells for oligomeric Ab aggregates as well as implementing machine learning and predictive modeling to enhance the utility of existing biomarkers. In the area of AD therapeutics, Professor Moss’ laboratory is investigating novel peptoid inhibitors that target both AD-associated neuroinflammation and aggregation of Ab. Research within Professor Moss’ laboratory has supported 3 master’s graduates, 15 doctoral graduates, and 4 current doctoral candidates, as well as 2 prior and 1 current postdoctoral researcher.
Professor Moss was an NSF Graduate Research Fellow and an American Heart Association (AHA) Postdoctoral Fellow. As a faculty member, she has been the recipient of an NSF CAREER Award, a New Investigator Research Award from the Alzheimer’s Association, and a Beginning Grant-In-Aid from AHA. Professor Moss has additionally been part of an NIH-funded COBRE center that explored the role of natural therapeutics. She has also been funded by NSF-BBE to study the evolution of early amyloid protein aggregates, by NSF-DMR to investigate rational design of nanoparticles as aggregation inhibitors, and by the NIH to investigate the propagation of Ab oligomers. Professor Moss received the 2012 Governor’s Young Scientist Award and was named a 2010 Rising Star by the University.
To learn more about Dr. Moss, please visit her profile.